MRI Services
MRI is a diagnostic imaging technology that uses a strong
magnet and radiofrequency waves to produce images of internal organs
and structures. Because MRI allows physicians to see inside the body
from any angle with great clarity, it can provide a wealth of information
for certain conditions faster and better than prior diagnostic imaging
studies. The accuracy and detail of images produced may also avoid the
need for exploratory surgeries.
The MRI equipment purchased by Neurology Associates is equipped with
a 1.0 tesla magnet. Its computerized work flow software allows for expedient,
streamlined studies. Our system also features MRA (Magnetic Resonance
Angiography) capabilities which allow for non-invasive, high-speed, 3-dimensional
imaging of blood vessels. These images are very useful to your physician
in evaluating diseases including blockages and aneurysms.
The speed and efficiency of this advanced equipment allows Neurology
Associates to schedule patients for MRI exams within days. A typical
MRI exam takes only 30 - 45 minutes to complete.
Brain Atrophy Metrics
In as much as progressive brain atrophy represents irreversible
brain damage and tissue loss, a metric of brain atrophy is a powerful
surrogate for the accumulated burden of disease. It is likely that brain
atrophy metrics will prove to be viable, precise, and clinically relevant
measures of disease burden in MS. Atrophy measures will lead to a better
understanding of MS pathology and will have important implications for
disease prognosis, and monitoring treatment effect in clinical trials.
Our technique is based on the automatic estimation
the BPF (brain parenchymal fraction). This measure depends on the 3D
estimatation of the grey-matter (GM), white-matter (WM) and cerebrospinal
fluid (CSF) intra-dural volumes from in vivo MRI data. Visible T2 or
T1 lesions explain only a minority of the variance in whole-brain or
GM atrophy, and none of the variance in WM atrophy. Patients with early
MS probably have normal neurological function despite significant brain
atrophy because the destructive pathologic process continues for a long
time before function is compromised. Nonetheless, Brain Atrophy predicts
and correlates with cognitive and physical disability better than any
other MRI measure. Findings imply an urgent need to identify factors
related to brain and spinal cord atrophy in MS. |